科研成果 |
发表SCI科研论文75篇，其中第一作者或通讯作者47篇。发表中文文章150余篇。获授权发明专利36项。出版著作7部，其中副主编4部，编者3部。 SCI文章： 1.Zhou B S, Liu J T, Wang Y R,Wu F L, Wang C X, Wang C Z, Liu, J P, Li P Y. Protective Effect of Ethyl Rosmarinate against Ulcerative Colitis in Mice Based on Untargeted MetabolomicsInt. J Mol Sci. 2022;23(3):1256. 2.Liu J L, Liu Y H, Yu H, Lin H Q, Zhang Y, Hsu ACY, Zhang M M, Sun W, Wang F, Li P Y, Liu, J P. Design, synthesis and biological evaluation of novel pyxinol derivatives with anti-heart failure activity. Biomedicine & Pharmacotherapy. 2021, 133:111050. 3.Liu Y H, Wang Z Y, Wang C X, Si H R, Yu H, Li L, Fu S Z, Tan L Y, Li P Y, Liu, J P, Zhao Y. Comprehensive phytochemical analysis and sedative-hypnotic activity of two Acanthopanax species leaves. Food & function. 2021;12(5):2292-2311. 4.Liu J L, Liu Y H, Lin H Q, Zhou B S, Yu H, Li L, Wang C X, Li X Y, Li P Y, Liu J P, Hao X H. The effect of ginsenoside Rg5, isolated from black ginseng, on heart failure in zebrafish based on untargeted metabolomics. Journal of Functional Foods. 2021, 76:104325. 5.WANG, C. Z., YUAN, Y. Z., PAN, H., HSU, A. C. Y., CHEN, J. L., LIU, J. P., LI, P. Y. & WANG, F. 2020. Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in Panax Genus, against Acetic Acid-Induced Gastric Ulcer in Rats Based on Untargeted Metabolomics. International Journal of Molecular Sciences, 21, 19. 6.FU, T. H., LIU, X. F., LIU, J. P., CAI, E. B., ZHAO, Y., LI, H. J., ZHANG, L. X., LI, P. Y. & GAO, Y. G. 2020. alpha-Mangostin exhibits antidepressant-like effects mediated by the modification of GABAergic, serotonergic and dopaminergic systems. Natural Product Research, 34, 868-871. 7.Zhang Y, Yu H, Fu S Z, Tan L Y, Liu J L, Zhou B S, Li L, Liu Y H, Wang C Z, Li P Y, Liu, J P. Synthesis and Anti-Hepatocarcinoma Effect of Amino Acid Derivatives of Pyxinol and Ocotillol. Molecules. 2021, 26(4):780 8.WANG, C., YUAN, Y., PAN, H., HSU, A. C. Y., CHEN, J., LIU, J., LI, P. & WANG, F. 2020. Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in Panax Genus, against Acetic Acid-Induced Gastric Ulcer in Rats Based on Untargeted Metabolomics. International journal of molecular sciences, 21, 2577. 9.TAN, J., LIU, J. L., WANG, H., ZHANG, Y., LIN, H. Q., WANG, N. Y., SI, H. R., ZHANG, Y. T., LIU, J. P., LI, P. Y. & SUN, K. 2020. Identification of blood-activating components from Xueshuan Xinmaining Tablet based on the spectrum-effect relationship and network pharmacology analysis. Rsc Advances, 10, 9587-9600. 10.YANG, N., WANG, H., LIN, O. Q., LIU, J. L., ZHOU, B. S., CHEN, X. L., WANG, C. Z., LIU, J. P. & LI, P. Y. 2020. Comprehensive metabolomics analysis based on UPLC-Q/TOF-MSE and the anti-COPD effect of different parts of Celastrus orbiculatus Thunb. Rsc Advances, 10, 8396-8420. 11.WANG, C. Z., DONG, Q. H., WU, F. L., LI, Z., LI, P. Y., LIU, J. P. & WANG, F. 2020. A new alkynol compound from Platycodins folium and its cytotoxicity. Natural Product Research, 7. 12.LIN, H. Q., ZHU, H. L., TAN, J., WANG, H., WANG, Z. Y., LI, P. Y., ZHAO, C. F. & LIU, J. P. 2019. Comparative Analysis of Chemical Constituents of Moringa oleifera Leaves from China and India by Ultra-Performance Liquid Chromatography Coupled with Quadrupole-Time-Of-Flight Mass Spectrometry. Molecules, 24, 25. 13.QI, Z., WANG, Z., ZHOU, B., FU, S., HONG, T., LI, P. & LIU, J. 2020. A new ocotillol-type ginsenoside from stems and leaves ofPanax quinquefoliumL. and its anti-oxidative effect on hydrogen peroxide exposed A549 cells. Natural Product Research, 34, 2474-2481. 14.LIN, H. Q., ZHU, H. L., TAN, J., WANG, H., DONG, Q. G., WU, F. L., LIU, Y. H., LI, P. Y. & LIU, J. P. 2019. Non-Targeted Metabolomic Analysis of Methanolic Extracts of Wild-Simulated and Field-Grown American Ginseng. Molecules, 24, 25. 15.QI, Z., LI, Z., GUAN, X. W., WANG, C. Z., WANG, F., LI, P. Y. & LIU, J. P. 2019. Four Novel Dammarane-Type Triterpenoids from Pearl Knots of Panax ginseng Meyer cv. Silvatica. Molecules, 24, 13. 16.WANG, C. Z., LIN, H. Q., YANG, N., WANG, H., ZHAO, Y., LI, P. Y., LIU, J. P. & WANG, F. 2019. Effects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics. Molecules, 24, 20. 17.LIN, H. Q., ZHU, H. L., TAN, J., WANG, C. Z., DONG, Q. H., WU, F. L., WANG, H., LIU, J. L., LI, P. Y. & LIU, J. P. 2019. Comprehensive Investigation on Metabolites of Wild-Simulated American Ginseng Root Based on Ultra-High-Performance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry. Journal of agricultural and food chemistry, 67, 5801-5819. 18.QI, Z., LI, W., TAN, J., WANG, C. Z., LIN, H. Q., ZHOU, B. S., LIU, J. P. & LI, P. Y. 2019. Effect of ginsenoside Rh-2 on renal apoptosis in cisplatin-induced nephrotoxicity in vivo. Phytomedicine, 61, 14. 19.ZHANG, K., LIU, Y., WANG, C. 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Protective effects of α-mangostin against acetaminophen-induced acute liver injury in mice. European journal of pharmacology, 827, 173-180. 31.YIN, Y. X., LIU, X. F., LIU, J. P., CAI, E. B., ZHU, H. Y., LI, H. J., ZHANG, L. X., LI, P. Y. & ZHAO, Y. 2018. Beta-sitosterol and its derivatives repress lipopolysaccharide/D-galactosamine-induced acute hepatic injury by inhibiting the oxidation and inflammation in mice. Bioorganic & Medicinal Chemistry Letters, 28, 1525-1533. 32.WANG, W. D., WANG, S. J., LIU, J. P., CAI, E. B., ZHU, H. Y., HE, Z. M., GAO, Y. G., LI, P. Y. & ZHAO, Y. 2018. Sesquiterpenoids from the root of Panax Ginseng protect CCl4-induced acute liver injury by anti-inflammatory and anti-oxidative capabilities in mice. Biomedicine & Pharmacotherapy, 102, 412-419. 33.WANG, W. D., ZHANG, Y. G., LI, H. J., ZHAO, Y., CAI, E. B., ZHU, H. Y., LI, P. Y. & LIU, J. P. 2018. 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Journal of Asian Natural Products Research, 9, 103-113. 专利： 1.刘云鹤,李乐,付书正,王钟瑶,谭璐瑩,王彩霞,余慧,李卓俏,李平亚,刘金平，2021，美花风毛菊总倍半萜内酯及制备方法和其药物用途，CN113350390A 2.刘云鹤,李乐,付书正,王钟瑶,谭璐瑩,王彩霞,余慧,李卓俏,李平亚,刘金平，2021，菴闾中总香豆素及制备方法和其药物用途，CN113230294A 3.林红强,余慧,王彩霞,李乐,周柏松,付书正,刘云鹤,谭璐瑩,刘金平,李平亚，2021，林下山西洋参在制备治疗抗生素相关性腹泻药物中的应用，CN113384609A 4.吴福林,陈小玲,史大臻,司函瑞,李乐,付书正,余慧,刘金平,李平亚，2021，原人参三醇PPT在制备抗血栓药物中的应用，CN112190585A 5.陈小玲,冯浩,司函瑞,吴福林,李乐,付东兴,刘俊彤,赖思含,刘金平,李平亚，2021，一种原人参三醇的结晶和单晶及其制备方法，CN113214338A 6.吴福林, 李平亚, 刘金平, 王德恒, 郭文英 & 李英杰，2019，止痛化癥胶囊的HPLC指纹图谱检测方法，CN108445125B 7.李平亚,郑茜,刘金平,张楠琪,王振洲,朱海林,陈金銮,张浩，2015，(20S,25R)-达玛-20,25-环氧-3β,12β,26,24β-四醇及其提取方法及医药用途，CN104761609A 8.王放，郑敬彤，路艳娇，张超，王国强，熊凌锌，关雪娃，陈芳，王婷，刘金平，酸浆苦素P在制备治疗慢性阻塞性肺病的药物中的应用，ZL201510680304.1 9.韩柳,李平亚,刘金平,李卓,郑茜，2015，达玛-20S,25S-环氧-3β, 12β, 26-三醇及其提取方法和药物用途，CN104693262A 10.李平亚,苏航,刘海燕,董刚,李卓,陈金銮,田旭,张庆贺,刘金平，2013，拟人参皂苷元R1及其提取方法和其药物用途，CN103193847A 11.李平亚,林美妤,韩柳,郑茜,李卓,刘海宇,王翠竹,刘金平，2013，拟人参皂苷RT6及其提取方法和其药物用途，CN103193848A 12.李平亚,刘金平，2013，一种西洋参果提取物的用途，CN102988441A 13.郝秀华,任媛媛,张庆贺,林美妤,刘海宇,李平亚,卢丹,刘金平，2012，达玛-20S, 25R-环氧-3β, 12β, 26-三醇及其提取方法和其药物用途，CN102329360A 14.李平亚,刘金平,任媛媛,刘传贵,胡军会,杜秀娟，2011，24(R)-拟人参皂苷元DQ的制备方法及其药物用途，CN102050860A 15.钟方丽,李平亚,刘金平,卢丹,赵岩,王晓林，2011，林下参皂苷B及其提取方法和其药物用途，CN102050864A 16.李平亚,刘金平,田旭,刘传贵,朱继忠,李丰，2011，拟人参皂苷RT5的提取方法及其药物用途，CN102010456A 17.李平亚,刘金平,刘传贵,金立群,张广民,闫智力,迟小娟，2011，一种伪人参皂苷GQ用途，CN102008498A 18.李平亚,刘金平,卢丹,刘传贵,杜秀娟,李丰，2011，20(R)-拟人参皂苷F11及其提取方法和其药物用途，CN101967170A 19.李平亚,刘金平,卢丹,刘传贵,杜秀娟,李丰，2011，人参皂苷R10及其提取方法和其药物用途，CN101948497A 20.李平亚,刘金平,卢丹,刘传贵,杜秀娟,李丰，2011，拟人参皂苷G2及其提取方法和其药物用途，CN101948498A 21.李平亚,刘金平,卢丹,刘传贵,杜秀娟,李丰，2011，拟人参皂苷G1及其提取方法和其药物用途，CN101948499A 22.刘金平,李平亚,卢丹,李艳娇，2010，西洋参皂苷F5ab及其提取方法和药物用途，CN101928320A 23.李平亚,刘金平,卢丹,薛健飞，2010，gartanin化合物在制备治疗高血脂症药物中的应用，CN101869559A 24.卢丹,李平亚,刘金平，2010，西洋参皂苷F6及其提取方法及其医药用途，CN101863945A 25.刘金平,李平亚,卢丹,薛健飞，2009，一种榛子素及其提取方法和药物用途，CN101613340 26.李平亚,卢丹,刘金平，2009，一种调节血脂的药物组合物，CN101584685 27.李平亚,刘金平,卢丹,周明娟，2009，刺五加果提取物在制备治疗高血脂症药物中的应用，CN101584719 28.刘金平,李平亚,卢丹,薛健飞，2009，榛子素B及其提取方法和其药物用途，CN101550125 29.卢丹,李平亚,刘金平,李海军，2009，5-羟甲基糠醛缩-5-糠醛甲醇及其制备方法及其医药用途，CN101544624 30.卢丹,李平亚,刘金平,李海军，2009，二缩(5-羟甲基糠醛)及其合成方法及其医药用途，CN101544654 31.李平亚,刘金平,卢丹,杜秀娟，2009，拟人参皂苷F11的医药用途，CN101524358 32.李平亚,刘金平，2009，拟人参皂苷F11的半合成方法，CN101519419 33.李平亚,卢丹,卢爱萍,刘金平,杜秀娟，2008，模拟移动床色谱拆分20(S)和20(R)-人参皂苷Rg3对映体，CN101230080 34.李平亚,刘金平，2005，伪人参皂苷－Pdq及其半合成方法和其药物用途，CN1706862 35.李平亚,赵文杰,刘金平，2004，人参果三醇组皂苷提取物及其提取、精制方法及其医药用途，CN1537863 36.李平亚,刘金平,卢丹，2004，西洋参果总皂苷提取物及其提取、精制方法及其医药用途，CN1482136 著作： 1.李平亚, 赵春芳, 刘金平. 2006. 猕猴桃的化学成分和生物活性研究进展, 吉林科学技术出版社. 2.张钧田, 李平亚, 卢丹, 刘金平. 2006. The Chemistry, Metabolism and Biological Activities of Ginseng, 化学工业出版社. 3.张钧田, 李平亚, 卢丹, 刘金平. 2008. 人参冠百草—人参化学、生物学活性和药代动力学研究进展, 化学工业出版社. 4.张辉, 李平亚, 冯家. 2010. 人参的功效与科学服用, 吉林出版集团有限责任公司. 5.李平亚, 刘金平, 卢丹. 2012. 人参皂苷 NMR 标准图谱, 化学工业出版社. 6.李平亚, 刘金平, 2017. 人参营养成分及功能因子, 化学工业出版社。 7.李平亚, 刘金平, 冯浩, 2019. 止痛化癥胶囊——药学·药效学·临床研究, 化学工业出版社. 8.杨洪军, 徐浩, 李平亚, 刘金平. 2020, 血脉双治-血栓心脉宁片现代研究, 人民卫生出版社. 9.李平亚, 刘金平. 2020, Ginseng Nutritional Components and Functional Factors, 斯普林格出版社. |
